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Treatment for vaginal dryness, painful sex, frequent UTIs, and urgency.


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Vaginal Estrogen

Explore a range of vaginal estrogen treatments. Prescribed after a simple consultation with a qualified doctor and delivered to your door.

Vaginal Estrogen Treatment

What Is Vaginal Estrogen?

Vaginal estrogen is a low-dose hormone therapy designed to target symptoms of menopause like vaginal dryness, irritation, and urinary issues.

Unlike systemic hormone treatments that affect the whole body, vaginal estrogen works locally to restore moisture and comfort. So it's a great option for women who do not want or cannot take systemic hormone therapy.

Vaginal estrogen is available as a vaginal cream, suppository, or ring. You can order a range of vaginal treatments online through Interlude.

Vaginal estrogen cream

Vaginal estrogen suppositories

Benefits of vaginal estrogen

Menopause leaves women vulnerable to vaginal dryness, frequent UTIs, urgency to pee, and leakage. It's what's medically known as the genitourinary syndrome of menopause.

Vaginal estrogen can help repair what menopause has taken away:

  • Relieves vaginal dryness and discomfort
  • Reduces urinary urgency and frequent UTIs
  • Improves skin moisture and elasticity

Who Can Use Vaginal Estrogen?

There are very few women who are not a good candidate for vaginal estrogen. It can be used for women experiencing symptoms due to hormonal changes in perimenopause, post-menopause, and post-partum. If you’re experiencing any of these symptoms, vaginal estrogen might be right for you:

  • Pain during intimacy
  • Burning or itching inside or outside the vagina
  • Unusual vaginal odor
  • Unexplained urinary tract infections (UTIs)
  • Frequent trips to the bathroom at night
  • Increased urinary urgency or leaking
  • Vaginal atrophy including shrinkage of the clitoris or labia

Note: Consult a healthcare provider, such as a board-certified doctor here at Interlude, to ensure that this treatment is right for you. Vaginal estrogen isn't available over-the-counter so you'll need a prescription. We make that part super simple with our online consult.

Vaginal Estrogen FAQ

  • How does vaginal estrogen work?

    Vaginal estrogen delivers a low dose of estrogen directly to the vaginal tissue, helping restore moisture, elasticity, and comfort.

  • Is vaginal estrogen safe?

    Vaginal estrogen treatment is beneficial because it releases a very low dose of estrogen directly into the vaginal area, without being absorbed significantly throughout the body. This means vaginal estrogen has fewer side effects and is a safe option, even for women who do not want or cannot take other forms of menopause hormone therapy.

    There is no evidence that vaginal estrogen increases the risk of cancer, cardiovascular disease, stroke, dementia, or any other serious problems.

    Source: The Menopause Society, The 2020 genitourinary syndrome of menopause position statement of The North American Menopause Society.
  • Can breast cancer survivors take vaginal estrogen?

    Yes. The American College of Obstetricians and Gynecologists supports the use of vaginal estrogen by breast cancer survivors.

    Source: The American College of Obstetricians and Gynecologists, Treatment of Urogenital Symptoms in Individuals With a History of Estrogen-dependent Breast Cancer.
  • Can I use vaginal estrogen on my face?

    While there is no estrogen cream that's FDA-approved for facial use, topical estrogen creams like vaginal estrogen are sometimes used sparingly on the face to help with skin changes associated with menopause.

    There is one study that shows that estrogen cream may increase collagen production on the face, which may combat the effects of aging skin. But more research is needed. As always, ask your healthcare provider before using your vaginal estrogen on your face.

    Source: Randomized Controlled Trial, Gynecol Endocrinol. 2017 Nov;33(11):845-848. doi: 10.1080/09513590.2017.1320708. Epub 2017 May 16.

Order Vaginal Estrogen Online With Prescription Included

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  1. Complete your health profile
  2. Within hours, our doctors review and contact you
  3. Your Rx ships same day

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