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Vaginal estradiol cream

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FAQ

Interlude

  • Who is Interlude for?

    If you are looking for specialized care for common menopause and post-menopause concerns, then Interlude is the place for you. Our team of medical specialists are experts in helping women to restore vaginal moisture, enjoy intimacy, prevent frequent UTIs, and stop urgent peeing.

  • Does Interlude replace my PCP or GYN?

    Interlude is a supplement to your once-yearly PCP or GYN appointments. We offer an easy and comfortable way to get a personalized care plan, prescription treatment, and unlimited followups.

  • How do I sign up?

    To get started you'll create a secure account and complete payment. Then you'll take an online assessment that will be reviewed by our medical team. A licensed MD or GYN will create a prescription and care plan that's customized to your needs.

    We are currently offering your first two months of prescription treatment for $15. After that, we'll ship refills for $59 every two months. Your initial treatment requires a one-time $69 online visit fee. Unlimited messaging and free shipping are included in your care with us.

My Account

  • Can I pay with my HSA?
    Yes! We accept payment by HSA or FSA. You can also visit your account to download a receipt for reimbursement.
  • How do I contact the support team?
    You can contact our amazing support team at support@getinterlude.com. We're here to help with any questions about your account, your shipments, and your payments. We're lighting fast at responding and you can expect a response within one day or less.
  • How do I contact my medical provider at Interlude?
    You can message your medical provider through your secure account at https://www.getinterlude.com/account. We aim to respond to all questions within one business day or less.

Medical care

  • What causes the genitourinary syndrome of menopause (GSM)?
    The vulva, vagina, urethra, labia, bladder, and clitoris are tissues in the body that become female because they contain estrogen. When your ovaries stop producing estrogen beginning in perimenopause, these tissues begin to atrophy. (We hate the word the word as much as you do. But atrophy is normal. And we're here to tell you that treatment is normal too.)
  • What are the symptoms of GSM?
    Also known as vulvar vaginal atrophy (VVA) or the genitourinary symptoms of menopause (GSM), vaginal atrophy is when the tissues feel dry, thin, too tight, or tender. You may notice changes in the shape of your vulva. You may even experience bleeding. As the tissues change due to lack of estrogen, the vagina produces less mositure, the vaginal canal shrinks, the vaginal folds lose elasticity, the clitoris becomes less prominent, blood flow and nerve sensation is reduced, and the urethra is exposed to abrasion and infection. This leads to painful sex, frequent UTIs, urgency to pee, yeast infections, loss of sexual pleasure, and discomfort in everyday activities. (Even wiping with toilet paper can be painful!)
  • Do you accept insurance?
    Due to government regulation for telemedicine, we do not accept insurance at this time. However, with rising out of pocket costs, high deductible plans, and high co-pays in the traditional health care system - our medical care is more affordable and accessible for most women - with or without insurance.

Medications

  • What medications does Interlude offer for GSM?
    We primarily offer vaginal estradiol cream. The North American Menopause Society states in 2020: "For bothersome genitourinary syndrome of menopause symptoms not relieved with over-the-counter therapies in women without indications for use of systemic hormone therapy, low-dose vaginal estrogen therapy or other therapies (eg, vaginal dehydroepiandrosterone or oral ospemifene) are recommended."
  • Does vaginal estradiol really work?
    Absolutely yes. Vaginal estradiol is applied to the vulva and the vaginal opening and restores moisture, plumpness, and elasticity to the tissues that have atrophied due to lack of estrogen.
  • Is vaginal estradiol safe?
    Unlike oral forms of estrogen, vaginal estradiol is prescribed in low doses and is minimally absorbed in the bloodstream. It has not been shown to increase the risk of cancer, stroke, or clot and women's health advocates have been lobbying the FDA to remove these warnings from the boxed safety information.
  • What are the benefits of a healthy vagina?
    As developments in modern medicine continue to extend life expectancy beyond the menopausal years, caring for the vulva and vagina can help extend the life of tissue - and thus extend your enjoyment of your moment in life. Maintaining a healthy vulva and vagina decreases the risk of urinary tract infections, decreases bothersome vaginal dryness, decreases pain with sex, and reduces frequency and burning with urination.
  • How long does it take to start feeling relief?
    Results are typically experienced within six to eight weeks of treatment. If symptoms are not beginning to subside after six to eight weeks, talk to your Interlude clinician. You may need a dose increase or adjustment. Checkins and messaging are included with your treatment and we look forward to helping you with any questions that come up.
  • When should I start taking vaginal estradiol?
    Women seeking medical therapy can start when symptoms are severe (usually 10 years post-menopause) or earlier. Keep in mind that some vulvar tissues can disappear entirely in the post-menopausal years. The labia minora, for example, can completely dissolve without estradiol. When this happens, the urethra may be exposed to abrasion or bacteria. Vaginal estradiol can prevent this much like sunscreen prevents sun damage.
  • How do you apply vaginal cream?
    Vaginal estradiol cream is applied as directed by your Interlude clinician - usually once daily for two weeks and then twice weekly. A plastic applicator comes with the medication, but women find that it wastes medication and is uncomfortable to insert into the vagina - especially if irritation is already present. Ask your Interlude clinician to help create a routine that suits your needs - it may be perfectly fine and sometimes even preferable to apply instead with your fingers to the affected areas of your vulva and vagina.
  • How do I get a prescription for vaginal estradiol?
    At Interlude we offer an online consultation with medical provider that's licensed in your state. All you need to do is take our online consultation. We'll pass your information along to a medical provider who will review your history and symptoms in detail and prescribe treatment if appropriate.

Shipments

  • Can I skip free shipping and get my prescription at my local pharmacy instead?
    Yes, you can get your prescription filled at your local pharmacy. Just email support@getinterlude.com and provide the name, address, and phone number of the pharmacy you wish to use. We'll notify your provider to change your prescription to your chosen pharmacy.
  • How long does my prescription last?
    Your one-time online visit fee covers up to 12 months or one year supply of refills. We ship refills every 2 months for $59 with free shipping. You can cancel or reschedule your shipment at any time from your secure account at https://www.getinterlude.com/account.
  • How do I cancel or reschedule my shipment?
    You can cancel or reschedule your shipment at any time from your secure account at https://www.getinterlude.com/account.