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What we offer

Treatment for vaginal dryness, painful sex, frequent UTIs, and urgency.


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Treat and prevent UTIs

At Interlude we offer medication that's prescribed online and specifically designed to treat and prevent UTIs through menopause and well beyond.
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Our board-certified doctors can treat:

Recurrent or
chronic UTIs
Pain with

Restore vaginal pH.
Protect the urinary tract.

Caring MDs

Rx treatments

As women age, hormones change, which can impact vaginal and urinary health. Prevent UTIs and UTI-like symptoms with vaginal estradiol. Antibiotic-free and clinically proven.

Vaginal estradiol cream

This doctor-prescribed topical cream prevents UTIs through menopause and well beyond. Applied twice weekly to the vagina and urethra.
Starting at
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Vaginal estradiol suppositories

This doctor-prescribed vaginal insert prevents UTIs through menopause and well beyond. Applied twice weekly to the vagina.
Starting at
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Free add-on

Treat your UTI today

Do you think you may have an active UTI? Get your UTI diagnosed online without going to the doctor's office.
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Within hours, a board-certified doctor will evaluate you for acute UTI symptoms.
If prescribed, antibiotics can be sent to a local pharmacy for same-day pickup.

How Interlude Works

Step 1

Get started with a prescription

Complete an online medical form with information about your symptoms and health history.

Online medical consultation for vaginal dryness
Step 2

Our doctors review your info

Within hours, we'll follow up by phone, video, or secure chat and write a prescription if appropriate.

Doctor prescribing estradiol vaginal cream to a patient who has vaginal atrophy from menopause
Step 3

Free delivery to your door

Your vaginal estradiol ships free with discreet packaging.

Estradiol vaginal cream delivered in a discreet box with free shipping


24/7 medical support.

Chat with our medical team at any time.


Find your reason to go with Interlude.
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UTIs in older women are characterized by lack of estrogen that causes changes in the vaginal pH and skin. You may notice recurrent UTIs, painful urination, urinary urgency, and urinary frequency. Or, you may feel UTI-like symptoms, but not have a UTI.

If you find yourself experiencing UTIs or UTI-like symptoms as you get older, vaginal estradiol may greatly reduce your risk of infection and improve your overall comfort. If appropriate, an antibiotic can also be prescribed.

  • What's the best way to prevent UTIs as you get older?

    When it comes to preventing UTIs, there are many options you can try - including low-dose antibiotics. But these carry the risk of antibiotic resistance. If you're in menopause and experiencing frequent UTIs, then vaginal estradiol can target the root cause. Vaginal estradiol prevents infection by rebalancing the vaginal pH and restoring the health of the tissues surrounding the urethra. In a recent study, 68% of post-menopausal women with recurrent UTIs treated with vaginal estradiol did not require additional therapy.

  • Why does menopause cause UTIs?

    UTIs in older women are often caused by decreased estrogen levels. Low estrogen can result in changes to the vaginal pH and the tissues surrounding the urethra, which increases risk of infection. To address frequent UTIs related to menopause, doctors can prescribe vaginal estradiol. This restores vaginal pH and improves the condition of the skin surrounding the urethra - thus preventing UTIs.

  • What's the difference between estradiol cream and estradiol inserts?

    Both estradiol cream and estradiol inserts are equally effective. Both are applied directly to the vagina. The choice between cream and tablets depends on personal preferences. Some individuals may find creams more comfortable to use, while others may prefer the simplicity of tablets.

  • How long do I take vaginal estradiol?

    Vaginal estradiol is applied twice a week and can be used for an extended duration to help prevent UTIs. It is important to note that discontinuing its use may result in the return of symptoms.

  • How do I get started with vaginal estradiol?

    To get started you'll create a secure account and complete payment. Then you'll take an online assessment that will be reviewed by our medical team. A licensed MD or GYN will create a prescription and we'll deliver it to your door.

    We are currently offering $20 off your first shipment of vaginal estradiol.

  • Can vaginal estradiol treat an existing infection?

    No, you'll need antibiotics to treat an acute UTI. As part of your care with us, we'll evaluate your symptoms for an acute UTI and help treat it whenever possible. If prescribed, we'll call in a one-time antibiotic prescription to your local pharmacy.

  • How can I get UTI antibiotics without visiting a doctor?

    As part of your care with us, we will evaluate your symptoms for an active UTI. Not all urinary symptoms are a UTI and that not all UTIs are appropriate for treatment through telemedicine. At Interlude we specialize in preventing UTIs. However, if you have an uncomplicated acute lower UTI, we'll call in a one-time antibiotic prescription to your local pharmacy. It's included with your vaginal estradiol prescription.

  • Do you take insurance?

    We are a cash pay health care service and we do not accept insurance at this time. However, with rising out of pocket costs, high deductible plans, and high co-pays in the traditional health care system - our medical care is more affordable and accessible for most women - with or without insurance.

Learn more about UTIs in menopause

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