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Treatment for vaginal dryness, painful sex, frequent UTIs, and urgency.


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Vaginal moisturizer with hyaluronic acid, aloe, and vitamin E
Vaginal moisturizer with hyaluronic acid, aloe, and vitamin E Vaginal moisturizer with hyaluronic acid, aloe, and vitamin E Vaginal moisturizer with hyaluronic acid, aloe, and vitamin E Vaginal moisturizer with hyaluronic acid, aloe, and vitamin E Interlude reviews Chart comparing hyaluronic acid vaginal moisturizer and estradiol vaginal cream

Hyaluronic+ Vaginal Cream

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This vaginal moisturizer with hyaluronic acid, vitamin E, and aloe is formulated to deeply hydrate, relieve vaginal dryness, and soothe irritation — without hormones. Ideal for women in perimenopause, menopause, or postpartum. Prescribed after a simple consultation with a qualified doctor, our Hyaluronic+ Vaginal Cream heals thin and dry skin at the cellular level. It's soothing, effective, and free from harsh additives.
Save $20 on your first order
  • 1 tube
  • 32 grams
$69 $49
Save $20
  • Online consult and prescription
  • One-time fee
Free shipping. Cancel anytime.

Medication information

  • What are the key ingredients?

    Our Hyaluronic+ Vaginal Cream is a non-hormonal, irritant-free vaginal moisturizer made with high-quality, soothing ingredients:

    • Hyaluronic Acid - Helps lock in moisture and relieve vaginal dryness
    • Aloe - Soothes and hydrates sensitive skin
    • Vitamin E - Supports skin barrier health and eases dryness
    • Clinical-grade cream base - Includes polyethylene glycol and mineral oil to aid absorption and application

    This vaginal moisturizer is freshly compounded to order in the United States in a 503A compounding pharmacy with PCAB Accreditation, ensuring quality and safety.

    You'll need a prescription for any compounded product in the United States. But we make that part super simple with a quick online consultation and prescription delivery.

  • How does this cream work?

    There are two types of feminine moisturizers on the market: vulvar moisturizers for external use and vaginal moisturizers for internal use. Many over-the-counter products are only safe for external use and may cause irritation if inserted vaginally.

    Our Hyaluronic+ Vaginal Cream is designed for to use as both a vulvar moisturizer or a vaginal moisturizer. It’s gentle, non-irritating, and delivers lasting moisture wherever you need it.

    For use as a vaginal moisturizer, the cream comes in an easy-to-use dispenser with a snap-on applicator. Just snap on the applicator, turn and click the dispenser, and then tilt off the applicator.

    The common dose is to insert 1-2 grams vaginally daily for 2 weeks. After that, insert 1 gram vaginally 1 to 3 times per week. 1 gram is 4 clicks.

    Follow the instructions from your Interlude-affiliated prescribing doctor.

  • Who can benefit from using this cream?

    Our Hyaluronic+ Vaginal Cream is formulated for women experiencing vaginal dryness — whether it's caused by postpartum hormone shifts, perimenopause, or post-menopause.

    When applied vaginally, hyaluronic acid helps:

    • Replenish vaginal moisture
    • Restore skin elasticity
    • Relieve symptoms like irritation, itching, or painful sex

    This hormone-free cream is ideal if:

    • You’re dealing with vaginal dryness due to estrogen loss
    • You want to boost moisture alongside vaginal estrogen treatment
    • You’re looking for a non-estrogen alternative to treat vaginal dryness

    One clinical study found that hyaluronic acid can be just as effective as vaginal estrogen for relieving dryness. (Although it won't restore the skin, balance pH, prevent UTIs, prevent urinary urgency, or prevent leakage like vaginal estrogen.)

  • When will I notice results?

    With consistent use, many patients notice a difference within 2 weeks. But everyone is different - so results may vary. Keep in mind this is not just about relief, but repairing the skin. It's not an overnight fix. Use as directed by your Interlude-affiliated doctor for lasting results!

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How It Works

Step 1

Complete your visit

After you complete checkout, you'll fill out a short health profile. Our medical team will review it to ensure you receive safe and effective care.
Interlude questionnaire form on a mobile phone
Step 2

Freshly compounded

Clinically-proven ingredients are freshly compounded just before shipping to you.
A board-certified physician working with Interlude
Step 3

Free delivery to your door

We'll ship your order directly to you, with ingredients that you can't get over-the-counter or in standard pharmacies.

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24/7 support

Questions? Just ask us! We're here for you. You can message our medical team at any time.

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