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Treatment for vaginal dryness, painful sex, frequent UTIs, and urgency.


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DHEA Vaginal Cream
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DHEA Vaginal Cream

DHEA 2%
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DHEA treats vaginal atrophy symptoms due to the genitourinary syndrome of menopause. Regular use helps restore vaginal tissue health, improve moisture, elasticity, and pH, and improve vaginal dryness and painful sex. Prescribed after a simple consultation with a qualified doctor, our DHEA Vaginal Cream is formulated with DHEA and a lightweight botanical gel cream base that's non-greasy and fast-absorbing.
  • 1 tube of cream
  • 3 month supply
$69 $49
Save $20
  • Online consult and prescription
  • One-time fee
Free 2-3 day shipping.

Medication information

  • Ingredients

    Our DHEA Vaginal Cream contains:

    • DHEA 2% is a hormone that naturally occurs in the body. When applied intravaginally, it is converted locally within vaginal tissue into both estrogen and testosterone, restoring moisture, elasticity, and pH.
    • Lightweight botanical base of purified water, carthamus tinctorius (safflower) oleosomes (plant-derived oil bodies/phytosomes containing linoleic and oleic acid triglycerides), polyacrylate-13, polyisobutene, sodium carbomer, polysorbate 20, tocopheryl acetate (Vitamin E), benzoic acid (preservative), sorbic acid (preservative).

    Your formula is freshly compounded in the United States in a 503A compounding pharmacy with PCAB Accreditation.

    Free of fragrances, dyes, parabens, mineral oil, sodium lauryl sulfate (SLS), propylene glycol, and 1,4-dioxane.

  • How to use

    This cream is dispensed with a convenient pump dispenser and applied to the vaginal opening and external vestibule with a clean fingertip.

    The typical dose is 1-2 pumps daily. Each pump delivers 0.25g of cream, which contains 5mg of DHEA. Follow the instructions from your Interlude-affiliated prescribing doctor.

  • Who is this cream for?

    Our DHEA Vaginal Cream is for women experiencing vaginal dryness, painful sex, or vulvovaginal atrophy from perimenopause or menopause.

    Because DHEA works locally, it offers meaningful symptom relief with minimal systemic hormone exposure.

    When applied intravaginally, DHEA is converted into estrogen and testosterone, leading to improvements in vaginal atrophy. Studies have shown that it doesn't lead to any meaningful increase in blood (serum) hormone levels.

  • When will I notice results?

    Many patients notice improvement in comfort and moisture within 2–4 weeks of consistent use. Full tissue restoration can take 8–12 weeks. Use as directed by your Interlude-affiliated doctor for lasting results.

How It Works

Step 1

Complete your visit

After you complete checkout, you'll fill out an online medical form.
Interlude questionnaire form on a mobile phone
Step 2

Custom prescription

A qualified doctor reviews your submission and follows up with information about your prescription.
A board-certified physician working with Interlude
Step 3

Free delivery to your door

We'll ship your formula directly to you, with freshly compounded ingredients.
DHEA vaginal cream delivered

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24/7 support

Questions? Just ask us! We're here for you. You can message our medical team at any time.

Benefits of DHEA vaginal cream

restore moisture icon

Restore moisture

rejuvenate tissues icon

Improve elasticity

enjoy intimacy icon

Ease painful sex

normalize ph icon

Normalize pH

As hormone levels decline in perimenopause and menopause, the vulva and vagina become thin and dry, leading to dryness, irritation, and painful sex.

When applied intravaginally, DHEA is converted locally into estrogen and testosterone, restoring the health of the vaginal tissues with minimal systemic hormone exposure. You'll need a prescription but we make that part super easy with an online consult and delivery to your door.

Reviews

We're rated Excellent on Trustpilot.

Transparent pricing

At Interlude, our goal is to make our pricing as easy and comfortable as the care we offer.

One-time consult fee
  • Easy online questionnaire
  • Reviewed by a licensed MD or GYN
  • Prescription good for 1 year
Treatment cost
$69 $49
  • Refills delivered every 3 months or at your selected frequency
  • Refill shipments are $69/tube
  • Text reminders before every refill in case you need to cancel or postpone
  • Reschedule or cancel anytime

Order your DHEA Vaginal Cream today

Free 2-3 day shipping with expedited options available.

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DHEA Vaginal Cream
DHEA Vaginal Cream