Treatment for vaginal dryness, painful sex, frequent UTIs, and urgency.
Treatment for vaginal dryness, painful sex, frequent UTIs, and urgency.
These highlights do not include all the information needed to use estradiol vaginal cream safely and effectively. Please see full prescribing information for estradiol vaginal cream.
Estradiol vaginal cream is a prescription medication that's FDA-approved to treat moderate to severe symptoms of vulvar and vaginal atrophy due to menopause. When you receive your vaginal estradiol (estrogen), you'll open the box and read an FDA warning that estrogens increase risk of cancer and heart disease. These warnings have only been substantiated with higher-dose oral forms of estrogen.
Estradiol vaginal cream is prescribed in very small doses and is applied only to the affected tissues. Vaginal estradiol is not shown to carry risk of cancer and heart disease. It can be safe for women with breast cancer, provided they have approval from their oncologist. Women's health groups and practicing clinicians have been lobbying the FDA to modify the confusing warnings.
At Interlude, we want you to feel safe and educated about your options for sexual wellness. If you are considering estradiol vaginal cream, our medical team will determine if you are a good candidate for vaginal estradiol cream. We're available 24/7 to answer any questions you may have - unlimited messaging is included with your treatment.
Estradiol vaginal cream (USP, 0.01%) is FDA-approved to treat moderate to severe dryness, itching, and burning in and around the vagina due to menopause. These changes are also known as vulvar and vaginal atrophy or the genitourinary syndrome of menopause.
Do not use vaginal estradiol if you:
Although estradiol vaginal cream is only used in and around the vagina, the risks associated with oral estrogens should be taken into account.
Less common but serious side effects of oral estrogen include:
These are some of the warning signs of serious side effects:
Call your healthcare provider right away if you get any of these warning signs, or any other unusual symptom that concerns you.
Common side effects include:
Other side effects:
These are not all the possible side effects of estradiol vaginal cream. For more information, ask your healthcare provider or pharmacist.
You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. Please see the full Prescribing Information, including the BOXED WARNING, for complete safety information.
