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Vaginal dryness? Meet hyaluronic acid. According to one study, 84% of women reported an improvement in vaginal dryness after 10 uses of hyaluronic acid.
Vaginal moisturizer with hyaluronic acid
At Interlude, we offer prescription-grade hyaluronic acid that's formulated without any irritating ingredients.
Choosing a hyaluronic acid vaginal moisturizer
Not sure which hyaluronic vaginal cream is right for you? At Interlude, we offer Hyaluronic+ Vaginal Cream and Soothing Estradiol Cream.
Our Hyaluronic+ Vaginal Cream contains additional soothing ingredients like aloe and vitamin E. It's non-hormonal, so it's a great option for women who do not want or cannot take vaginal estrogen.
Our Soothing Estradiol Cream is an all-in-one vaginal estrogen and vaginal moisturizer that soothes skin while repairing signs of vaginal dryness. Hyaluronic acid relieves dryness, while estradiol helps repair thin and dry skin. It can also prevent issues that are related to vaginal dryness - like frequent UTIs or urgency to pee.
Hyaluronic+ Vaginal Cream | Soothing Estradiol Cream |
---|---|
Non-hormonal | Ultra low dose of estrogen |
Best for women who do not want or cannot use vaginal estrogen | Best for women who want an all-in-one vaginal moisturizer and vaginal estrogen |
Treats vaginal dryness | Treats vaginal dryness, prevents UTIs, stops urgency and leaking |
Moisturizes vaginal skin at the cellular level | Moisturizes vaginal skin at the cellular level |
Can be used internally and/or externally | Can be used internally and/or externally |
No parabens, sulfates, propylene glycol, or irritating ingredients | No parabens, sulfates, propylene glycol, or irritating ingredients |
Why we love hyaluronic acid for vaginal health
Hyaluronic acid is known as a humectant - meaning it is a substance that retains moisture. When applied internally to the vaginal skin, hyaluronic acid works by hydrating the top layer of the vaginal skin surface.


As a vaginal moisturizer, hyaluronic acid is a compelling solution for several reasons.
- The body naturally produces hyaluronic acid. It helps to keep joints and tissues lubricated and moisturized.
- Hyaluronic acid has been clinically studied as a vaginal moisturizer, and there is emerging evidence to show it is comparable to vaginal estrogen with regard to effectively restoring moisture.
- Side effects from hyaluronic acid are rare. It’s generally safe to use even if you do not want or cannot take other hormonal options such as vaginal estrogen.
Next steps
In summary, if you’re looking to alleviate vaginal dryness, a non-hormonal vaginal moisturizer with hyaluronic acid could be a great place to start.
For women with persistent vaginal dryness after non-hormonal treatments, treatment with vaginal estrogen may offer greater benefit. Vaginal estrogen works to target the underlying cause of vaginal dryness - which can explain why it may be more effective both in relieving vaginal dryness and in alleviating the myriad of other vaginal and urinary symptoms that arise from loss of estrogen after menopause.
If you’re experiencing vaginal dryness, we can help at Interlude. We offer prescription treatment and caring MDs and GYNs to support you on a path to optimal vaginal and urinary health after menopause.